The cylinder capacity of the aspirated engine was brought to the limit of the regulations with 4493 cc in time for the Italian GP at Monza on 2 September 1950, where Ascari finished second, after his car stopped and he took Serafini’s, sharing the points.

The first win finally came on 14 July 1951 in the English GP at Silverstone. The Argentinean José Froilàn Gonzalez managed to beat the Alfa Romeos, taking the 375 F1 to victory. Two weeks later, Ascari won the German Grand prix and, later, at Monza. But it wasn’t enough to overtake Fangio for the drivers’ title, due to the defeat at Barcellona when the tyres gave out.

Type front, longitudinal 60° V12
Bore/stroke 80 x 74.5 mm
Unitary displacement 374.47 cc
Total displacement 4493.73 cc
Compression ratio 11 : 1
Maximum power 257 kW (350 hp) at 7000 rpm
Power per litre 78 hp/l
Maximum torque -
Valve actuation single overhead camshaft per bank, two valves per cylinder
Fuel feed three Weber 42 DCF carburettors
Ignition single spark plug per cylinder, two Marelli magnetos
Lubrication dry sump
Clutch multi-plate
Frame tubular steel
Front suspension independent, unequal-length wishbones, lower transverse leaf spring, Houdaille hydraulic shock absorbers
Rear suspension de Dion, lower transverse leaf spring, twin radius arms, Houdaille hydraulic shock absorbers
Brakes drums
Transmission 4-speed + reverse
Steering worm and sector
Fuel tank capacity 195 litres
Front tyres 5.50 x 16
Rear tyres 7.50 x 17